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Disulfide exchange: exposing supramolecular reactivity through dynamic covalent chemistry

Journal

CHEMICAL SOCIETY REVIEWS
Volume 43, Issue 6, Pages 1861-1872

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cs60326a

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Funding

  1. Engineering and Physical Sciences Research Council
  2. Foundation for Polish Science [HOMING PLUS/2012-6/14]

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A Tutorial Review of the subtle supramolecular interactions influencing the outcomes of equilibrating systems, focusing on the dynamic covalent chemistry (DCC) of disulfide exchange reactions, is presented. We discuss the topics of cation-pi interactions (2.1), hydrophobic effects (2.2), hydrogen bonding interactions (2.3) aromatic donor-acceptor interactions (2.4), and metal-ligand interactions (2.5) in the context of dynamic disulfide chemistry.

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