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Palladium-catalysed cross-coupling of organosilicon reagents

Journal

CHEMICAL SOCIETY REVIEWS
Volume 41, Issue 5, Pages 1845-1866

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cs15181a

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The palladium catalysed cross-coupling of organosilicon reagents with organo halides and pseudo-halides has developed over the past 30 years into an efficient and attractive carbon-carbon bond forming strategy. Extensive research within this field to expand and diversify on the scope of the organosilicon coupling reaction will continue to promote its use in the synthesis of biologically and pharmaceutically important organic molecules. The recent advances made within this area are explored in this critical review (199 references).

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