Journal
CHEMICAL SOCIETY REVIEWS
Volume 41, Issue 2, Pages 632-642Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cs15143f
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Funding
- National Natural Science Foundation of China [91027035]
- National Natural Science of China [20933007]
- Fundamental Research Funds for the Central Universities [WK1013002]
- Shanghai Institutions of Higher Learning
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Recently dark-field microscopy and Rayleigh scattering spectroscopy have emerged as complementary technologies for ultrasensitive biological detection and imaging with high spatial and temporal resolution. Plasmonic resonant nanoparticles are key nano-scale probes for these technologies that have enabled single-molecule sensitivity and imaging. In this tutorial review, we focus on the use of plasmonic probes as single-particle biological nanosensors in vitro and in vivo. The progress in this field over the last decade will be highlighted.
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