4.8 Review

Recent progress in fluorescent and colorimetric chemosensors for detection of amino acids

Journal

CHEMICAL SOCIETY REVIEWS
Volume 41, Issue 1, Pages 52-67

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cs15159b

Keywords

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Funding

  1. National Research Foundation of Korea (NRF) [2010-0018895]
  2. Ministry of Education, Science and Technology [2010K001202]
  3. Ewha Womans University

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Due to the biological importance of amino acids, the development of optical probes for these molecules has been an active research area in recent years. This tutorial review focuses on recent contributions since the year 2000 concerning the fluorescent or colorimetric sensors for amino acids, and is organized according to their structural classification and reaction types. For reaction based chemosensors, the works are classified according to the mechanisms between sensors and amino acids, including imine formation, Michael addition, thiazinane or thiazolidine formation, cleavage of a sulfonate ester, cleavage of disulfide, metal complexes-displace coordination and others.

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