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A new route to diverse 1-azasugars from N-boc-5-hydroxy-3-piperidene as a common building block
H Ouchi et al.
JOURNAL OF ORGANIC CHEMISTRY (2005)
Multicomponent domino processes based on the organocatalytic generation of conjugated acetylides:: Efficient synthetic manifolds for diversity-oriented molecular construction
D Tejedor et al.
CHEMISTRY-A EUROPEAN JOURNAL (2005)
Amino acid catalyzed direct enantioselective formation of carbohydrates:: one-step de novo synthesis of ketoses
I Ibrahem et al.
TETRAHEDRON LETTERS (2005)
Amino acid-catalyzed direct enantioselective synthesis of β-amino-α-oxyaldehydes
I Ibrahem et al.
TETRAHEDRON LETTERS (2005)
Synthesis of chiral vicinal diamines by highly diastereoselective three-component phenolic Mannich reaction: Temperature-dependent stereodivergency
C Rondot et al.
ORGANIC LETTERS (2005)
Diastereocontrolled multicomponent pathway to 3,4-heterocycle-annulated tetrahydro-β-carbolines
E Dardennes et al.
TETRAHEDRON-ASYMMETRY (2005)
Diastereoselective Petasis Mannich reactions accelerated by hexafluoroisopropanol: a pyrrolidine-derived arylglycine synthesis
KK Nanda et al.
TETRAHEDRON LETTERS (2005)
Room temperature ionic liquids from 20 natural amino acids
K Fukumoto et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)
Chemical constituents from the hulls of Oryza sativa with cytotoxic activity
IM Chung et al.
CHEMISTRY OF NATURAL COMPOUNDS (2005)
Catalytic asymmetric synthesis of a potent thiomarinol antibiotic
X Gao et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)
Highly enantioselective phenyl transfer to aryl aldehydes catalyzed by easily accessible chiral tertiary aminonaphthol
JX Ji et al.
JOURNAL OF ORGANIC CHEMISTRY (2005)
Digoniodiol, deoxygoniopypyrone A, and goniofupyrone A:: Three new styryllactones from Goniothalamus amuyon
YH Lan et al.
PLANTA MEDICA (2005)
Macrocycles rapidly produced by multiple multicomponent reactions including bifunctional building blocks (MiBs)
Ludger A. Wessjohann et al.
MOLECULAR DIVERSITY (2005)
A novel highly selective chiral auxiliary for the asymmetric synthesis of L- and D-α-amino acid derivatives via a multicomponent Ugi reaction
A Basso et al.
JOURNAL OF ORGANIC CHEMISTRY (2005)
Glyco- and peptidomimetics from three-component Joullie-Ugi coupling show selective antiviral activity
TM Chapman et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)
Synthesis of functionalized heterocycles via a tandem Staudinger/aza-Wittig/Ugi multicomponent reaction
MSM Timmer et al.
TETRAHEDRON-ASYMMETRY (2005)
Dihydroxyacetone in amino acid catalyzed Mannich-Type reactions
B Westermann et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2005)
1,3-Dipolar cycloadditions of carbonyl ylides to aldimines: A three-component approach to syn-alpha-hydroxy-beta-amino esters
S Torssell et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2005)
Direct catalytic enantioselective aza-Diels-Alder reactions
H Sunden et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2005)
Asymmetric multicomponent reactions (AMCRs): The new frontier
DJ Ramon et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2005)
Asymmetric synthesis of selectively protected amino sugars and derivatives by a direct organocatalytic Mannich reaction
D Enders et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2005)
The direct catalytic asymmetric cross-Mannich reaction:: A highly enantioselective route to 3-amino alcohols and α-amino acid derivatives
A Córdova
CHEMISTRY-A EUROPEAN JOURNAL (2004)
Synthesis of C-glycosyl β-amino acids by asymmetric Mannich-type three-component reactions
A Dondoni et al.
TETRAHEDRON LETTERS (2004)
The tethered Biginelli condensation in natural product synthesis
ZD Aron et al.
CHEMICAL COMMUNICATIONS (2004)
Multicomponent reactions are accelerated in water
MC Pirrung et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)
New interlocked molecules generated from a podand containing urea units and imidazolium salts using an anion template
B Tomapatanaget et al.
TETRAHEDRON LETTERS (2004)
U-4C-3CR versus U-5C-4CR and stereochemical outcomes using suitable bicyclic β-amino acid derivatives as bifunctional components in the Ugi reaction
A Basso et al.
TETRAHEDRON LETTERS (2004)
Discovery of a novel bicycloproline P2 bearing peptidyl α-ketoamide LY514962 as HCV protease inhibitor
Y Yip et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2004)
A highly active 4-siloxyproline catalyst for asymmetric synthesis
Y Hayashi et al.
ADVANCED SYNTHESIS & CATALYSIS (2004)
Titanium catalysis in the Ugi reaction of α-amino acids with aromatic aldehydes
T Godet et al.
ORGANIC LETTERS (2004)
Synthesis of a polymer-bound galactosylamine and its application as an immobilized chiral auxiliary in stereoselective syntheses of piperidine and amino acid derivatives
G Zech et al.
CHEMISTRY-A EUROPEAN JOURNAL (2004)
Chemical approaches towards synthesis of some naturally occurring iminosugars
T Ayad et al.
CURRENT ORGANIC CHEMISTRY (2004)
Three-component Staudinger-type stereoselective synthesis of C-glycosyl-β-lactams and their use as precursors for C-glycosyl isoserines and dipeptides.: A polymer-assisted solution-phase approach
A Dondoni et al.
ADVANCED SYNTHESIS & CATALYSIS (2004)
Catalytic enantio- and diastereoselective aldol reactions of glycine-derived silicon enolate with aldehydes:: An efficient approach to the asymmetric synthesis of anti-β-hydroxy-α-amino acid derivatives
J Kobayashi et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)
The scope of the direct proline-catalyzed asymmetric addition of ketones to imines
W Notz et al.
ADVANCED SYNTHESIS & CATALYSIS (2004)
β-lactam synthesis by Ugi reaction of β-keto acids in aqueous solution
MC Pirrung et al.
SYNLETT (2004)
Synthesis and antiviral properties of arabino and ribonucleosides of 1,3-dideazaadenine, 4-nitro-1,3-dideazapurine and diketopiperazine
S Sinha et al.
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS (2004)
Design of a nonreductive method for chemoselective cleavage of hydrazines in the presence of unsaturations:: Application to a stereoconvergent three-component synthesis of (-)-methyl palustramate
BB Touré et al.
JOURNAL OF ORGANIC CHEMISTRY (2004)
A concise asymmetric synthesis of the ADE fragment of nakadomarin
KA Ahrendt et al.
ORGANIC LETTERS (2004)
Stereochemical control of the Passerini reaction
PR Andreana et al.
ORGANIC LETTERS (2004)
Structure-based exploration of cyclic dipeptide chitinase inhibitors
DR Houston et al.
JOURNAL OF MEDICINAL CHEMISTRY (2004)
A short synthesis of (+/-)-cytisine
C Botuha et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2004)
Enantioselective total syntheses of the Ipecacuanha alkaloid emetine, the Alangium alkaloid tubulosine and a novel benzoquinolizidine alkaloid by using a domino process
LE Tietze et al.
CHEMISTRY-A EUROPEAN JOURNAL (2004)
Domino reactions in the synthesis of heterocyclic natural products and analogs
LF Tietze et al.
PURE AND APPLIED CHEMISTRY (2004)
Three-component sequential aza[4+2] cycloaddition/allylboration/retro-sulflnyl-ene reaction: A new stereocontrolled entry to palustrine alkaloids and other 2,6-disubstituted piperidines
BB Toure et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2004)
Asymmetric catalytic coupling of organoboranes, alkynes, and imines with a removable (trialkylsilyloxy)ethyl group-direct access to enantiomerically pure primary allylic amines
SJ Patel et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2004)
Readily available biaryl P,N ligands for asymmetric catalysis
TF Knopfel et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2004)
Direct catalytic enantioselective alpha-aminomethylation of ketones
I Ibrahem et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2004)
A planning strategy for diversity-oriented synthesis
MD Burke et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2004)
Towards organo-click chemistry: Development of organocatalytic multicomponent reactions through combinations of Aldol, Wittig, Knoevenagel, Michael, Diels-Alder and Huisgen cycloaddition reactions
DB Ramachary et al.
CHEMISTRY-A EUROPEAN JOURNAL (2004)
4-alkylidene-azetidin-2-ones: Novel inhibitors of leukocyte elastase and gelatinase
G Cainelli et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2003)
Comprehensive survey of combinatorial library synthesis: 2002
RE Dolle
JOURNAL OF COMBINATORIAL CHEMISTRY (2003)
Structural basis of the lisinopril-binding specificity in N- and C-domains of human somatic ACE
JH Fernandez et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
3-boronoacrolein as an exceptional heterodiene in the highly enantio- and diastereoselective Cr(III)-catalyzed three-component [4+2]/allylboration
X Gao et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)
The generation of dihydropyrimidine libraries utilizing Biginelli multicomponent chemistry
CO Kappe
QSAR & COMBINATORIAL SCIENCE (2003)
Combinatorial libraries of chiral ligands for enantioselective catalysis
C Gennari et al.
CHEMICAL REVIEWS (2003)
Catalytic enantioselective addition of allylic organometallic reagents to aldehydes and ketones
SE Denmark et al.
CHEMICAL REVIEWS (2003)
Recent advances in solution-phase multicomponent methodology for the synthesis of heterocyclic compounds
RVA Orru et al.
SYNTHESIS-STUTTGART (2003)
Chemistry of α-aminonitriles.: Part 39.: 2,6-diamino-5,8-diaza-7,9-dicarba-purine
ZJ Wang et al.
ORGANIC LETTERS (2003)
Synthesis and reactivity of N-protected-α-amino aldehydes
D Gryko et al.
CHIRALITY (2003)
Recent advances in the synthesis of piperidones and piperidines
PM Weintraub et al.
TETRAHEDRON (2003)
Cytotoxic styrylpyrones from Goniothalamus amuyon
YH Lan et al.
JOURNAL OF NATURAL PRODUCTS (2003)
Carbon-carbon bond forming reactions mediated by silicon Lewis acids
AD Dilman et al.
CHEMICAL REVIEWS (2003)
A convenient, one-step synthesis of optically active tertiary aminonaphthol and its applications in the highly enantioselective alkenylations of aldehydes
JX Ji et al.
JOURNAL OF ORGANIC CHEMISTRY (2003)
Synthesis of dihydroxylated prolines and iminocyclitols from five-membered endocyclic enecarbamates.: Total synthesis of the potent glycosidase inhibitor (2R,3R,4R,5R)-2,5-dihydroxymethyl-3,4-dihydroxypyrrolidine (DMDP)
ALL Garcia et al.
TETRAHEDRON LETTERS (2003)
Paraherquamides, brevianamides, and asperparalines: Laboratory synthesis and biosynthesis. An interim report
RM Williams et al.
ACCOUNTS OF CHEMICAL RESEARCH (2003)
Interaction of the mitotic inhibitor monastrol with human kinesin Eg5
S DeBonis et al.
BIOCHEMISTRY (2003)
Immobilized nicotinic receptor stationary phases: going with the flow in high-throughput screening and pharmacological studies
R Moaddel et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2003)
Synthesis of chiral 2′,3′-pyranone(pyrrolidinone)-fused tryptamines
E Dardennes et al.
TETRAHEDRON LETTERS (2003)
Diversity-oriented synthesis; a challenge for synthetic chemists
DR Spring
ORGANIC & BIOMOLECULAR CHEMISTRY (2003)
Organocatalytic asymmetric domino Knoevenagel/Diels-Alder reactions: A bioorganic approach to the diastereospecific and enantioselective construction of highly substituted spiro[5,5]undecane-1,5,9-triones
DB Ramachary et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2003)
Recent advances in the activation of boron and silicon reagents for stereocontrolled allylation reactions
JWJ Kennedy et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2003)
Highly enantioselective organocatalytic conjugate addition of malonates to acyclic alpha,beta-unsaturated enones
N Halland et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2003)
Enantioselective, copper(I)-catalyzed three-component reaction for the preparation of propargylamines
N Gommermann et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2003)
Directed evolution of an amine oxidase possessing both broad substrate specificity and high enantioselectivity
R Carr et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2003)
Multi-component reactions : Emerging chemistry in drug discovery 'From xylocain to crixivan'
C Hulme et al.
CURRENT MEDICINAL CHEMISTRY (2003)
Nitrogen inversion in cyclic amines and the bicyclic effect
AM Belostotskii et al.
JOURNAL OF ORGANIC CHEMISTRY (2002)
Synthesis and antituberculosis activity of C-phosphonate analogues of decaprenolphosphoarabinose, a key intermediate in the biosynthesis of mycobacterial arabinogalactan and lipoarabinomannan
CA Centrone et al.
JOURNAL OF ORGANIC CHEMISTRY (2002)
Recent progress in the asymmetric synthesis of α-substituted propargylamines
J Blanchet et al.
ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL (2002)
Synthesis of novel chiral ligands from amino acids by the Ugi reaction
G Dyker et al.
TETRAHEDRON-ASYMMETRY (2002)
Evidence that monastrol is an allosteric inhibitor of the mitotic kinesin Eg5
Z Maliga et al.
CHEMISTRY & BIOLOGY (2002)
New meroterpenoids from the ascidian Aplidium conicum
L Garrido et al.
JOURNAL OF NATURAL PRODUCTS (2002)
Design and synthesis of a novel class of sugar-peptide hybrids:: C-linked glyco ß-amino acids through a stereoselective acetate Mannich reaction as the key strategic element
C Palomo et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2002)
Peptidotriazoles on solid phase: [1,2,3]-triazoles by regiospecific copper(I)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azides
CW Tornoe et al.
JOURNAL OF ORGANIC CHEMISTRY (2002)
Studies on novel peptidomimetics having bi-directional dispositions of hydroxylated D-Pro-Gly motifs anchored on a C2-symmetric iminosugar-based foundation
TK Chakraborty et al.
JOURNAL OF ORGANIC CHEMISTRY (2002)
Ammonium chloride-promoted four-component synthesis of pyrrolo[3,4-b]pyridin-5-one
P Janvier et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2002)
Recent developments of transition-state analogue glycosidase inhibitors of non-natural product origin
VH Lillelund et al.
CHEMICAL REVIEWS (2002)
Recent developments in the chemistry of dihydropyridines
R Lavilla
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 (2002)
Efficient proline-catalyzed Michael additions of unmodified ketones to nitro olefins
B List et al.
ORGANIC LETTERS (2001)
Towards the synthesis of C-glycosylated dihydropyrimidine libraries via the three-component Biginelli reaction.: A novel approach to artificial nucleosides
A Dondoni et al.
TETRAHEDRON LETTERS (2001)
β-hydroxy-γ-lactones as chiral building blocks for the enantioselective synthesis of marine natural products
C García et al.
JOURNAL OF ORGANIC CHEMISTRY (2001)
Diastereocontrolled Strecker reaction using (S)-5-phenylmorpholin-2-one
LM Harwood et al.
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 (2001)
Pharmacophore model for antiepileptic drugs acting on sodium channels
SM Tasso et al.
JOURNAL OF MOLECULAR MODELING (2001)
Stereochemically controlled syntheses of indole-substituted dihydrofuran-2-ones and a pyrrolidin-2-one
M Boisbrun et al.
TETRAHEDRON LETTERS (2000)
Recent advances in the Biginelli dihydropyrimidine synthesis. New tricks from an old dog
CO Kappe
ACCOUNTS OF CHEMICAL RESEARCH (2000)
Methods for anomeric carbon-linked and fused sugar amino acid synthesis: The gateway to artificial glycopeptides
A Dondoni et al.
CHEMICAL REVIEWS (2000)
A short catalytic enantioselective synthesis of the proinflammatory eicosanoid 12(R)-hydroxy-5(Z),8(Z),10(E),14(Z)-eicosatetraenoic acid (12(R)-HETE)
XJ Han et al.
ORGANIC LETTERS (2000)
Synthesis of enantiopure α,α-disubstituted amino acids from the asymmetric Strecker reaction products of aldehydes
DW Ma et al.
ORGANIC LETTERS (2000)
Metal-mediated synthesis of medium-sized rings
L Yet
CHEMICAL REVIEWS (2000)
Expansion to seven-membered rings
EJ Kantorowski et al.
TETRAHEDRON (2000)
Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells
JL Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Sugar-mimic glycosidase inhibitors: natural occurrence, biological activity and prospects for therapeutic application
N Asano et al.
TETRAHEDRON-ASYMMETRY (2000)
Target-oriented and diversity-oriented organic synthesis in drug discovery
SL Schreiber
SCIENCE (2000)
Catalytic asymmetric Strecker synthesis.: Preparation of enantiomerically pure α-amino acid derivatives from aldimines and tributyltin cyanide or achiral aldehydes, amines, and hydrogen cyanide using a chiral zirconium catalyst
H Ishitani et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2000)
Molecular requirements of imino sugars for the selective control of N-linked glycosylation and glycosphingolipid biosynthesis
TD Butters et al.
TETRAHEDRON-ASYMMETRY (2000)
Improved synthesis of isogranulatimide, a G2 checkpoint inhibitor. Syntheses of didemnimide C, isodidemnimide A, neodidemnimide A, 17-methylgranulatimide, and isogranulatimides A-C
E Piers et al.
JOURNAL OF ORGANIC CHEMISTRY (2000)
Cyclo(Dehydroala-L-Leu), an alpha-glucosidase inhibitor from Penicillium sp F70614
OS Kwon et al.
JOURNAL OF ANTIBIOTICS (2000)
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