4.8 Review

Recent developments in natural product synthesis using metal-catalysed C-H bond functionalisation

Journal

CHEMICAL SOCIETY REVIEWS
Volume 40, Issue 4, Pages 1885-1898

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cs15013h

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Funding

  1. Philip and Patricia Brown
  2. Astra-Zeneca
  3. Pfizer
  4. EPSRC
  5. Engineering and Physical Sciences Research Council [EP/I002065/1, EP/I00548X/1] Funding Source: researchfish
  6. EPSRC [EP/I002065/1, EP/I00548X/1] Funding Source: UKRI

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Metal-catalysed C-H bond functionalisation has had a significant impact on how chemists make molecules. Translating the methodological developments to their use in the assembly of complex natural products is an important challenge for the continued advancement of chemical synthesis. In this tutorial review, we describe selected recent examples of how the metal-catalysed C-H bond functionalisation has been able to positively affect the synthesis of natural products.

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