4.8 Review

DNA origami: a quantum leap for self-assembly of complex structures

Journal

CHEMICAL SOCIETY REVIEWS
Volume 40, Issue 12, Pages 5636-5646

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cs15057j

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Funding

  1. Danish National Research
  2. Office of Naval Research
  3. Army Research Office
  4. National Science Foundation
  5. Department of Energy
  6. National Institutes of Health
  7. US Department of Energy, Office of Science, Office of Basic Energy Sciences [DE-SC0001016]
  8. NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM088818] Funding Source: NIH RePORTER

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The spatially controlled positioning of functional materials by self-assembly is one of the fundamental visions of nanotechnology. Major steps towards this goal have been achieved using DNA as a programmable building block. This tutorial review will focus on one of the most promising methods: DNA origami. The basic design principles, organization of a variety of functional materials and recent implementation of DNA robotics are discussed together with future challenges and opportunities.

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