Journal
CHEMICAL SOCIETY REVIEWS
Volume 39, Issue 6, Pages 2120-2135Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b925092a
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Funding
- Ministry of Education, Science and Technology [20090083065, 20090063001]
- WCU program [R31-2008-000-10180-0]
- NSF of China [20725621]
- National Basic Research Program of China [2009CB724706]
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Due to the biological importances of thiols, such as cysteine, homocysteine and glutathione, the development of optical probes for thiols has been an active research area in recent few years. This critical review focuses on the fluorescent or colorimetric sensors for thiols according to their unique mechanisms between sensors and thiols, including Michael addition, cyclization with aldehyde, cleavage of sulfonamide and sulfonate ester by thiols, cleavage of selenium-nitrogen bond by thiols, cleavage of disulfide by thiols, metal complexes-oxidation-reduction, metal complexes-displace coordination, nano-particles and others.
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