Journal
CHEMICAL SOCIETY REVIEWS
Volume 38, Issue 6, Pages 1647-1662Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b804436h
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Funding
- National Institutes of Health [GM 58908]
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM058907] Funding Source: NIH RePORTER
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Traditional analyte-specific synthetic receptors or sensors have been developed on the basis of supramolecular interactions (e. g., hydrogen bonding, electrostatics, weak coordinative bonds). Unfortunately, this approach is often subject to limitations. As a result, increasing attention within the chemical sensor community is turning to the use of analyte-specific molecular indicators, wherein substrate-triggered reactions are used to signal the presence of a given analyte. This tutorial review highlights recent reaction-based indicator systems that have been used to detect selected anions, cations, reactive oxygen species, and neutral substrates.
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