Journal
CHEMICAL SOCIETY REVIEWS
Volume 38, Issue 6, Pages 1598-1607Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b805648j
Keywords
-
Categories
Funding
- Spanish Ministerio de Educacion y Ciencia [MEC CTQ2007-60494/BQU]
- Spanish MAE-AECI
Ask authors/readers for more resources
The Negishi cross-coupling of organozinc reagents is a valuable tool for the formation of C-C bonds in the presence of functional groups. Although this reaction is catalysed by Ni or Pd complexes, the latter have been much more developed. Nevertheless, Ni derivatives have become important in recent years, especially for their activity in the formation of alkyl-alkyl bonds. The mechanisms involved in Ni-catalysed reactions are different from the usual catalytic cycle involving oxidative addition-transmetalation-reductive elimination that is generally accepted for Pd-catalysed reactions. This tutorial review presents the more recent advances in Ni-catalysed Negishi cross-couplings for the formation of different kinds of C-C bonds and discusses their proposed reaction mechanisms.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available