Journal
CHEMICAL SOCIETY REVIEWS
Volume 37, Issue 4, Pages 839-864Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b714519e
Keywords
-
Categories
Ask authors/readers for more resources
In discovering the remarkable catalytic properties of BINOL-derived phosphoramidites (binoP-NR2), Dutch researchers recently achieved a long-awaited breakthrough in asymmetric catalysis. For the first time, easily accessible monodentate chiral P(III) ligands turned out to provide high enantioselectivities when used in rhodium-catalysed olefin hydrogenation. The simplest ligand representative of this family is MonoPhos (TM), which can be made straightforwardly from BINOL and hexamethylphosphorous triamide. Since the first publication dealing with such catalysts (J. Am. Chem. Soc., 2000), a variety of binoP-NRR' ligands have been reported in which the amino group bears a functional substituent or a stereogenic centre. This critical review examines the impact of the presence of such a functionality in the amino group on catalytic olefin hydrogenation reactions.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available