Journal
CHEMICAL PHYSICS LETTERS
Volume 461, Issue 4-6, Pages 189-192Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.cplett.2008.06.077
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A single wall carbon nanohorn (SWNH) is a new kind of single-graphene tubules with a diameter of 2-5 nm and a length 40-50 nm. In this work, we used oxidized SWNH (SWNHox) to incorporate vancomycin hydrochloride (VCM) for its controlled release by taking advantage of the interactions between VCM and SWNHox. Phospholipid-poly(ethylene glycol) was used to modify the hydrophobic surface of SWNHox to improve its dispersion in aqueous systems. In the release study using this complex, a stable release of VCM was achieved for an extended period. (C) 2008 Elsevier B.V. All rights reserved.
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