Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 54, Issue 8, Pages 2442-2446Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201408614
Keywords
BODIPY; fluorescent probes; imaging agents; live neurons
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Funding
- A*STAR Biomedical Research Council
- Singapore Ministry of Education Academic Research Fund Tier 2 [MOE2010-T2-1-025]
- NGS Scholarship
- A*STAR Graduate Scholarship
- Duke-NUS SRP Phase 2 Research Block Grant
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To address existing limitations in live neuron imaging, we have developed NeuO, a novel cell-permeable fluorescent probe with an unprecedented ability to label and image live neurons selectively over other cells in the brain. NeuO enables robust live neuron imaging and isolation invivo and invitro across species; its versatility and ease of use sets the basis for its development in a myriad of neuronal targeting applications.
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