Journal
CHEMICAL COMMUNICATIONS
Volume 54, Issue 73, Pages 10371-10374Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8cc04954h
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Funding
- JSPS KAKENHI Grant [26893223, 15K18899, 16H05103]
- MEXT [26111012]
- Daiichi Sankyo Foundation of Life Science
- Grants-in-Aid for Scientific Research [16H05103, 15K18899, 26111012, 26893223] Funding Source: KAKEN
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Nitroxyl (HNO) is a gaseous molecule with unique pharmacological functions distinct from those of nitric oxide. Because HNO is highly reactive with biological molecules, spatiotemporally controllable HNO releasers are required. Herein, we report the first visible-light-controllable HNO releasers, based on caged Piloty's acid, and we demonstrate their applicability in living cells.
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