Journal
CHEMICAL COMMUNICATIONS
Volume 54, Issue 81, Pages 11391-11394Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8cc05690k
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Funding
- National Natural Science Foundation of China [81772593, 21235003, J1210026]
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By employing DNA nanoflower blooming in the nanochannels of porous anodic alumina (PAA), a nanochannel platform for microRNA (miRNA) detection has been proposed. Significant steric and electrostatic hindrance of the miRNA-initiated DNA-nanoflower growth may also amplify the signal readout for miRNA detection to give excellent sensitivity, selectivity and reproducibility.
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