4.7 Article

Targeted theranostic prodrugs based on an aggregation-induced emission (AIE) luminogen for real-time dual-drug tracking

Journal

CHEMICAL COMMUNICATIONS
Volume 50, Issue 78, Pages 11465-11468

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc05255b

Keywords

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Funding

  1. Singapore National Research Foundation [R-279-000-390-281]
  2. Ministry of Defense [R279-000-340-232]
  3. Singapore-MIT Alliance of Research and Technology (SMART) [R279-000-378-592]
  4. JCO [IMRE/12-8P1103]
  5. Research Grants Council of Hong Kong [HKUST2/CRF/10, N_HKUST620/11]

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A targeted theranostic delivery system containing two prodrugs with drug tracking and activation monitoring functions was developed for visualizing cancer cell ablation with synergistic anticancer effects.

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