Journal
CHEMICAL COMMUNICATIONS
Volume 50, Issue 96, Pages 15202-15205Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc07487d
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Funding
- Worldwide Cancer Research [06-0539, 09-0591]
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Biophysical studies of ligand interactions with three human telomeric repeat sequences (d(AGGG(TTAGGG)(n), n = 3, 7 and 11)) show that an oxazole-based 'click' ligand, which induces parallel folded quadruplexes, preferentially stabilises longer telomeric repeats providing evidence for selectivity in binding at the interface between tandem quadruplex motifs.
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