4.7 Article

A facilely synthesized amino-functionalized metal-organic framework for highly specific and efficient enrichment of glycopeptides

Journal

CHEMICAL COMMUNICATIONS
Volume 50, Issue 78, Pages 11504-11506

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc05179c

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Funding

  1. National Natural Science Foundation of China [21275009]

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A facilely synthesized amino-functionalized metal-organic framework (MOF) MIL-101(Cr)-NH2 was first applied for highly specific glycopeptide enrichment based on the hydrophilic interactions. With the special characteristics of the MOF, the material performed well in selectivity and sensitivity for both standard glycoprotein samples and complex biological samples.

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