4.7 Article

Water-stable metal-organic frameworks with intrinsic peroxidase-like catalytic activity as a colorimetric biosensing platform

Journal

CHEMICAL COMMUNICATIONS
Volume 50, Issue 9, Pages 1092-1094

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc48398c

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Funding

  1. National Natural Science Foundation of China [21371162, 51301159]
  2. National Key Basic Research Program of China [2014CB931803]
  3. Research Fund for the Doctoral Program of Higher Education of China [20133402120020]
  4. Chinese Academy of Sciences
  5. University of Science and Technology of China (USTC)

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Two iron(III)-based metal-organic frameworks (MOFs) are found to behave as efficient peroxidase mimics and catalyze the oxidation of different peroxidase substrates by H2O2 accompanied with significant color change in the solution. With these findings, a simple and sensitive colorimetric assay to detect H2O2 and ascorbic acid has been established.

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