4.7 Article

Multifunctional upconverting nanoparticles for near-infrared triggered and synergistic antibacterial resistance therapy

Journal

CHEMICAL COMMUNICATIONS
Volume 50, Issue 72, Pages 10488-10490

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc04584j

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Funding

  1. National Basic Research Program of China [2011CB936004, 2012CB720602]
  2. National Natural Science Foundation of China [21301169, 91213302, 21210002]

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To integrate photodynamic therapy with photothermal therapy for improved multidrug-resistant bacteria therapy, we have constructed a novel multifunctional core/satellite nanostructure by decorating CuS nanoparticles onto the surface of NaYF4:Mn/Yb/Er@photosensitizer doped SiO2. This system exhibited a superior antibacterial activity towards drug-resistant Staphylococcus aureus and Escherichia coli.

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