4.7 Article

Mitochondria-targeted colorimetric and fluorescent probes for hypochlorite and their applications for in vivo imaging

Journal

CHEMICAL COMMUNICATIONS
Volume 50, Issue 63, Pages 8640-8643

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc02673j

Keywords

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Funding

  1. National Program on Key Basic Research Project of China (973 Program) [2012CB720603, 2013CB328900]
  2. National Science Foundation of China [21232005, 21321061, J1310008, J1103315]
  3. Specialized Research Fund for the Doctoral Program of Higher Education in China [20120181130006]

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Two mitochondria-targeted real-time probes were presented, which could selectively respond to hypochlorite over other ROS. Meanwhile, the off-on probes could be successfully applied in the in vivo imaging of hypochlorite in living mice.

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