4.7 Article

The design and synthesis of a hydrophilic core-shell-shell structured magnetic metal-organic framework as a novel immobilized metal ion affinity platform for phosphoproteome research

Journal

CHEMICAL COMMUNICATIONS
Volume 50, Issue 47, Pages 6228-6231

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc01038h

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Funding

  1. 973 Project [2013CB911201, 2012CB910602]
  2. 863 Project [2012AA020202]
  3. National Natural Science Foundation of China [21075022, 20875017, 21105016]

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In this work, polydopamine (PDA)-coated magnetic microspheres with surface modification of zirconium-based MOFs were synthesized for the first time. The as-synthesized Fe3O4@PDA@Zr-MOF composites were successfully applied as a novel immobilized metal ion affinity platform for phosphoproteome research.

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