Journal
CHEMICAL COMMUNICATIONS
Volume 50, Issue 23, Pages 3044-3047Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc49790a
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Funding
- National Research Foundation of Korea [2009-0081566]
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Biotin-disulfide-coumarin conjugates are designed and synthesized as novel fluorescent sensors for cancer targeted intracellular thiol imaging in living organisms. In vitro experiments disclose that probe 6 is preferentially taken up by biotin receptor-positive A549 tumor cells through receptor mediated endocytosis.
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