4.7 Article

Aptamer-mediated 'turn-off/turn-on' nanozyme activity of gold nanoparticles for kanamycin detection

Journal

CHEMICAL COMMUNICATIONS
Volume 50, Issue 100, Pages 15856-15859

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc07275h

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Funding

  1. Commonwealth of Australia for the Australian Research Council Future Fellowship [FT140101285]
  2. Endeavour Research Award

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A new ultrafast and highly sensitive 'turn-off/turn-on' biosensing approach that combines the intrinsic peroxidase-like activity of gold nanoparticles (GNPs) with the high affinity and specificity of a ssDNA aptamer is presented for the efficient detection of a model small molecule kanamycin.

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