☆ 4.7 Article

Simultaneous elimination of carryover contamination and detection of DNA with uracil-DNA-glycosylase-supplemented loop-mediated isothermal amplification (UDG-LAMP)

CHEMICAL COMMUNICATIONS (2014)

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Journal

CHEMICAL COMMUNICATIONS
Volume 50, Issue 28, Pages 3747-3749

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc00540f

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Categories

Chemistry, Multidisciplinary

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We report a one-pot, closed-vessel enzymatic assay that eliminates carryover contamination while preserving robust DNA amplification in loop-mediated isothermal amplification (LAMP), providing reliable and rapid detection of target DNA in contaminated samples.

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