4.7 Article

Palladium-catalyzed R2(O)P directed C(sp2)-H acetoxylation

Journal

CHEMICAL COMMUNICATIONS
Volume 50, Issue 36, Pages 4686-4689

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc01238k

Keywords

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Funding

  1. NSFC [21272100]
  2. Program for Changjiang Scholars, the Innovative Research Team in University [PCSIRT: IRT1138]
  3. Program for New Century Excellent Talents in University [NCET-11-0215, lzujbky-2013-k07]

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A novel and efficient Pd-catalyzed C-H acetoxylation is described. The approach uses R-2(O)P as a directing group to synthesize various substituted 2'-phosphorylbiphenyl-2-OAc compounds. Notably, the reaction exhibits smooth operation under mild conditions and shows good functional group tolerance. Products are obtained with high selectivity and yields.

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