4.7 Article

Enzymatic preparation of a redox-responsive hydrogel for encapsulating and releasing living cells

Journal

CHEMICAL COMMUNICATIONS
Volume 50, Issue 44, Pages 5895-5898

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc49766f

Keywords

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Funding

  1. Japan Society for the Promotion of Science (JSPS) [25289297]
  2. Ministry of Education, Culture, Sports, Science, and Technology of Japan [24226019]
  3. Research Fellowships of JSPS for Young Scientists [24-5940]
  4. Grants-in-Aid for Scientific Research [12J05940] Funding Source: KAKEN

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Horseradish peroxidase-mediated oxidative cross-linking of a thiolated poly(ethylene glycol) is promoted in the absence of exogenous hydrogen peroxide, by adding a small amount of a phenolic compound under physiological conditions. The prepared hydrogel can encapsulate and release living mammalian cells.

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