4.7 Article

Highly specific enrichment of N-linked glycopeptides based on hydrazide functionalized soluble nanopolymers

Journal

CHEMICAL COMMUNICATIONS
Volume 50, Issue 8, Pages 1027-1029

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc47347c

Keywords

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Funding

  1. National Science and Technology Key Project of China [2012CB910602, 2012AA020203, 2012CB910103]
  2. NSFC [21025519, 21335002, 31070732]
  3. PhD Programs Foundation of Ministry of Education of China [20130071110034]
  4. China Postdoctoral Science Foundation

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In this work, for the first time, hydrazide functionalized PAMAM was designed and synthesized for efficient and selective enrichment of N-linked glycopeptides from complex biological samples using FASP (filter-aided sample preparation) mode.

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