4.7 Article

Synergistic dual-targeting hydrogel improves targeting and anticancer effect of Taxol in vitro and in vivo

Journal

CHEMICAL COMMUNICATIONS
Volume 50, Issue 97, Pages 15423-15426

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc05614k

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Funding

  1. National Natural Science Foundation of China [81173023]
  2. College Graduate Scientific Research and Innovation Program of JiangSu Province of China [KYLX_0616]

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A synergistic dual-targeting molecular self-assembly hydrogel was designed with estrone (Et) and Arg-Gly-Asp (RGD) peptide. Confocal imaging in vitro and real-time visualization in vivo researches were carried out to evidence enhanced targeted delivery and anticancer effect of Taxol.

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