Journal
CHEMICAL COMMUNICATIONS
Volume 50, Issue 24, Pages 3197-3200Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc00091a
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Funding
- CRI project [2009-0081566]
- Basic Science Research Program from the National Research Foundation of The Ministry of Science, ICT & Future Planning in Korea [2012R1A1A2006259]
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Two novel Cu2+ sensors, 1 and 2, bearing naphthalimide and a DPA moiety were synthesized to study copper accumulation in organelles by selective Cu2+ sensing. The ER-selective Cu2+ sensor 1 that we developed serves as a valuable tool for understanding the subcellular compartmentalization and roles of copper ions in physiology and pathophysiology.
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