Journal
CHEMICAL COMMUNICATIONS
Volume 50, Issue 78, Pages 11523-11525Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc05558f
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Funding
- Swiss National Science Foundation [PP00P2_133568]
- University of Zurich
- Stiftung fur Wissenschaftliche Forschung of the University of Zurich
- L. & Th. La Roche Stiftung
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Zr-89-based imaging agents hold great promise as novel radio-tracers in nuclear medicine. However, insufficient stability of currently used radiometal complexes in vivo is a safety concern for clinical applications. We herein report the first octadentate bifunctional chelating agent for the development of Zr-89-labelled (bio) conjugates with improved stability.
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