Journal
CHEMICAL COMMUNICATIONS
Volume 50, Issue 81, Pages 12173-12176Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc05394j
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Funding
- National Science Foundation of China [21172272, 91213302, 81330077, 21272291]
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A novel 2,4,5-triaryl-substituted imidazole (IZCM-1) has been found to display distinct and specific fluorescence enhancement upon binding to parallel G-quadruplexes. Such a sensitive and topology-specific probe is able to light up without affecting the topology or thermal stability of the G-quadruplex sample. Thus, these advantages distinguish IZCM-1 from other G-quadruplex probes.
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