Journal
CHEMICAL COMMUNICATIONS
Volume 50, Issue 15, Pages 1909-1911Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc48518h
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Funding
- National Natural Science Foundation of China [21325523, 21075129]
- Award for the Hundred Talent Program of the Chinese Academy of Science
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A telomere-triggered isothermal exponential amplification-based DNAzyme biosensor is developed for highly sensitive detection of telomerase in cancer cells even at the single-cell level. This biosensor can be further applied for the screening of telomerase inhibitors for anticancer drug development.
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