4.7 Article

Detection of the ovarian cancer biomarker CA-125 using chemiluminescence resonance energy transfer to graphene quantum dots

Journal

CHEMICAL COMMUNICATIONS
Volume 50, Issue 11, Pages 1344-1346

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc47701k

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Funding

  1. NSF [EPS 1003907]
  2. West Virginia University Research Corporation
  3. West Virginia EPSCoR Office
  4. Office Of The Director
  5. Office of Integrative Activities [1003907] Funding Source: National Science Foundation

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An immunoassay has been developed for the detection of the ovarian cancer biomarker CA-125 by utilizing the chemiluminescence resonance energy transfer to graphene quantum dots. This biosensor shows a wide linear range from 0.1 U mL(-1) to 600 U mL(-1) with a limit of detection of 0.05 U mL(-1) for CA-125 in a buffer solution.

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