Journal
CHEMICAL COMMUNICATIONS
Volume 50, Issue 78, Pages 11533-11535Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc05462h
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Funding
- IISER Pune
- Department of Biotechnology, India [BT/05/IYBA/2011]
- Council for Scientific and Industrial Research (CSIR)
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We describe here hitherto unexplored chemistry of the sulfinate ester functional group as being highly selective towards nucleophilic substitution by thiols at physiological pH. Using this cleavable trigger, an optical thiol probe that is suitable for thiol bioimaging has been developed.
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