4.7 Article

A small molecule two-photon fluorescent probe for intracellular sodium ions

Journal

CHEMICAL COMMUNICATIONS
Volume 50, Issue 11, Pages 1309-1312

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc48342h

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Funding

  1. National Research Foundation (NRF)
  2. Korean Government [2011-0028663]
  3. Priority Research Centers Program through the NRF [2009-0093826]

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We report a small-molecule two-photon fluorescent probe (ANa2) for Na+ that shows a strong TPEF enhancement in response to Na+ and can be easily loaded into live cells and can real time monitor the fluctuation of [Na](i) in live cells and living tissue at more than 100 mu m depth.

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