Journal
CHEMICAL COMMUNICATIONS
Volume 50, Issue 23, Pages 3103-3105Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc49003c
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Funding
- National Institutes of Health [GM079359, CA133086]
- National Key Scientific Program of China [2011CB911000]
- NSFC [21221003]
- China National Instrumentation Program [2011YQ03012412]
- National Natural Science Foundation of China [20934004, 91127046]
- National Basic Research Program of China (NBRPC) [2012CB821500, 2010CB934500]
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A therapeutic aptamer-lipid-poly(lactide-co-glycolic acid) hybrid nanoparticle-based drug delivery system was prepared and characterized. This system can co-deliver two different drugs with distinct solubility and different anticancer mechanisms to target cancer cells with high specificity and efficiency.
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