Journal
CHEMICAL COMMUNICATIONS
Volume 50, Issue 40, Pages 5313-5315Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc47444e
Keywords
-
Categories
Funding
- Hong Kong Baptist University [FRG2/1213/ 021]
- Centre for Cancer and Inflammation Research, School of Chinese Medicine (CCIR-SCM, HKBU)
- Health and Medical Research Fund [HMRF/13121482]
- Research Grants Council [HKBU/201811, HKBU/204612, HKBU/201913]
- French National Research Agency/Research Grants Council Joint Research Scheme [A-HKBU201/12]
- Science and Technology Development Fund, Macao SAR [103/2012/A3, 001/2012/A]
- University of Macau [MYRG091(Y2-L2)-ICMS12-LCH, MYRG121(Y2-L2)-ICMS12-LCH)]
Ask authors/readers for more resources
A label-free, oligonucleotide-based, switch-on luminescence detection method for T4 polynucleotide kinase activity has been developed using a novel G-quadruplex-selective luminescent Ir(III) complex probe. The application of the assay for screening potential T4 PNK inhibitors is also demonstrated. To our knowledge, this is the first metal-based assay for PNK activity.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
