Journal
CHEMICAL COMMUNICATIONS
Volume 50, Issue 45, Pages 5967-5969Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc01005a
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Funding
- Ministry of Education, Culture, Sports, Science, and Technology (MEXT), Japan
- Grants-in-Aid for Scientific Research [24118008] Funding Source: KAKEN
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Cyclic naphthalene diimide 1 bound to hybrid-type tetraplex DNA from 5'AGGG(TTAGGG)(3)-3' (K = 8.6 x 106 M-1) with 260-fold greater affinity than binding to a double stranded oligonucleotide consisting of 5'-GGG AGG TTT CGC-3' and 3'-CCC TCC AAA GCG-5' (nK = 3.3 x 104 M-1) with 0.5 mu M of IC50 for telomerase activity.
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