4.7 Article

Versatile ruthenium(II)-catalyzed C-H cyanations of benzamides

Journal

CHEMICAL COMMUNICATIONS
Volume 50, Issue 15, Pages 1878-1881

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc49502g

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Funding

  1. European Research Council under the European Community's Seventh Framework Program (FP7)/ERC [307535]
  2. Chinese Scholarship Council

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Direct cyanations of arenes and heteroarenes bearing only weakly coordinating amides were accomplished using a robust ruthenium(II) catalyst. The user-friendly C(sp(2))-H activation occurred with the assistance of carboxylate with high site-selectivity, excellent functional group tolerance and ample scope.

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