4.7 Article

Metal-free oxidative synthesis of quinazolinones via dual amination of sp3 C-H bonds

Journal

CHEMICAL COMMUNICATIONS
Volume 50, Issue 49, Pages 6471-6474

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc02648a

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Funding

  1. National Natural Science Foundation of China [21272114, 91313303]
  2. National Natural Science Fund for Creative Research Groups [21121091]

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A novel metal-free synthesis of quinazolinones via dual amination of sp(3) C-H bonds was developed. The sp(3) carbon in methylarenes or adjacent to a heteroatom in DMSO, DMF or DMA was used as the one carbon synthon.

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