4.7 Article

Catalytic hydrogenation of amino acids to amino alcohols with complete retention of configuration

Journal

CHEMICAL COMMUNICATIONS
Volume 50, Issue 50, Pages 6656-6659

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc02675f

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Funding

  1. Grants-in-Aid for Scientific Research [14J03554] Funding Source: KAKEN

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Rh-MoOx/SiO2 is an effective heterogeneous catalyst for selective hydrogenation of amino acids to amino alcohols in a water solvent. MoOx modification of Rh drastically enhanced the activity and improved the selectivity and ee. Various amino alcohols were obtained in high yields (90-94%) with complete retention of configuration.

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