4.7 Article

Enzyme-free fluorescent-amplified aptasensors based on target-responsive DNA strand displacement via toehold-mediated click chemical ligation

Journal

CHEMICAL COMMUNICATIONS
Volume 50, Issue 8, Pages 991-993

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc48064j

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Funding

  1. Japan Society for the Promotion of Science (JSPS) [24510165]
  2. Grants-in-Aid for Scientific Research [24510165] Funding Source: KAKEN

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A new target-responsive DNA strand displacement system via toehold-mediated click chemical ligation was designed and prepared for enzyme-free fluorescent-amplified aptasensors. The aptasensors significantly amplified fluorescent signals in response to targets based on target recycling processes.

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