Journal
CHEMICAL COMMUNICATIONS
Volume 50, Issue 36, Pages 4699-4702Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc49870k
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Funding
- National Natural Science Foundation of China [21174060]
- Fundamental Research Funds for the Central Universities [1116020509]
- Program for Changjiang Scholars and Innovative Research Team in University [IRT1252]
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Dextran modified with pendant acetals is used to load doxorubicin (DOX) and a near-infrared-emissive conjugated polymer (BTTPF), and this aims to provide selective drug release at therapeutic targets including tumors. The BTTPF is applicable to tracking the anticancer drug release through the change of Forster resonance energy transfer efficiency between doxorubicin and BTTPF during degradation of the nanoparticles in vivo.
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