Journal
CHEMICAL COMMUNICATIONS
Volume 50, Issue 15, Pages 1875-1877Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc48860h
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- Max-Planck Society
- European Research Council (ERC Advanced Grant AUTOHEPARIN)
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Dermatan sulfates are glycosaminoglycan polysaccharides that serve a multitude of biological roles as part of the extracellular matrix. Orthogonally protected D-galactosamine and L-iduronic acid building blocks and a photo-cleavable linker are instrumental for the automated synthesis of dermatan sulfate oligosaccharides. Conjugation-ready oligosaccharides were obtained in good yield.
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