4.7 Article

A highly selective water-soluble optical probe for endogenous peroxynitrite

Journal

CHEMICAL COMMUNICATIONS
Volume 50, Issue 69, Pages 9947-9950

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc04192e

Keywords

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Funding

  1. National Program on Key Basic Research Project of China (973 Program) [2012CB720603, 2013CB328900]
  2. National Science Foundation of China [21232005, 21321061, J1310008, J1103315]
  3. Specialized Research Fund for the Doctoral Program of Higher Education in China [20120181130006]

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A colorimetric and fluorescent probe C-Py-1 for ONOO- was prepared and it could exhibit high sensitivity and excellent selectivity toward ONOO- among reactive oxygen species (ROS) and reactive nitrogen species (RNS) with a rapid response time in 100% water solution. Meanwhile, C-Py-1 was successfully applied in the imaging of endogenous ONOO- in RAW264.7 cells.

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