Journal
CHEMICAL COMMUNICATIONS
Volume 50, Issue 12, Pages 1465-1468Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc47590e
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Funding
- National Natural Science Foundation of China [21272149]
- Innovation Program of Shanghai Municipal Education Commission [14ZZ094]
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A copper-mediated multi-component reaction was developed through isocyanide insertion into N-H bonds of less active secondary arylamines. This approach leads to an efficient synthesis of unsymmetrical tetrasubstituted ureas in one pot.
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