4.7 Article

Tuneable Fmoc-Phe-(4-X)-Phe-NH2 nanostructures by variable electronic substitution

Journal

CHEMICAL COMMUNICATIONS
Volume 50, Issue 73, Pages 10630-10633

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc04926h

Keywords

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Funding

  1. European Research Council under the European Union's Seventh Framework Programme (FP7)/EMERgE/ERC Grant [258775]
  2. Linn Products Ltd
  3. FP7 Marie Curie Actions [289723]

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Supramolecular structures were produced by in situ enzymatic condensation of Fmoc-Phe-(4-X), where X denotes electron with-drawing or donating groups, with Phe-NH2. The relative contribution of pi-stacking and H-bonding interactions can be regulated by the nature of X, resulting in tuneable nanoscale morphologies.

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