Journal
CHEMICAL COMMUNICATIONS
Volume 50, Issue 26, Pages 3427-3430Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc47738j
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Funding
- Japan Society for the Promotion of Science (JSPS) [24681028, 25650053]
- NSF CAREER Award [DMR-0845592]
- Department of Biologic and Materials Sciences
- University of Michigan School of Dentistry
- NIH [GM084018, GM095640]
- Grants-in-Aid for Scientific Research [25650053] Funding Source: KAKEN
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM095640, R01GM084018] Funding Source: NIH RePORTER
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The function and mode of action of curcumin in modulating the formation of lipid raft domains were investigated by microscopic observation using model membranes. Curcumin induces fusion of lipid raft domains at extremely low concentrations through the alteration of the boundary between the ordered and disordered phases.
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