4.7 Article

Mn(II)/O2-promoted oxidative annulation of vinyl isocyanides with boronic acids: synthesis of multi-substituted isoquinolines

Journal

CHEMICAL COMMUNICATIONS
Volume 50, Issue 88, Pages 13485-13488

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc06427e

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Funding

  1. National Natural Science Foundation of China [21272149]
  2. Innovation Program of Shanghai Municipal Education Commission [14ZZ094]

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An efficient manganese(II)/O-2-promoted oxidative radical cascade reaction was developed for the modular synthesis of multi-substituted isoquinolines from easily accessible vinyl isocyanides and boronic acids.

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